Determine the anticancer activity of green synthesized MgO nanoparticles by Spirogyra varians

Abstract

Algae samples were taken from 2nd February to 21st April 2023. Various parameters including temperature, acidity, turbidity, electricity, and the presence of nutrients such as nitrogen (NO3) and phosphorus (PO3) were recorded. Following the identification of Spirogyra varians, an algal extraction was conducted using methanol as the solvent. The algal extract was utilized to synthesize Mgo nanoparticles (MgONPs), 0.05 M concentrations of Mg(NO₃)₂H₂O with a reaction degree equal to 80º at 6 pH were used as conditions of the green synthesized. The green-generated MgONPs were characterized using UV-Vis, FESEM, EDS, and XRD techniques. The anticancer efficacy against MCF-7 breast cancer cells and its correlation with Reactive Oxygen Species (ROS) were assessed. The findings demonstrated significant efficacy and impact of the produced magnesium oxide nanoparticles (MgONPs) against MCF-7 breast cancer cells. Additionally, a clear correlation was seen between MgONPs and reactive oxygen species (ROS) in the cancer cell line.